The Indian Medical Parliamentarians’ Forum (IMPF), a group of 45 doctors who are also members of Parliament, has raised a serious warning. They say children with rare Lysosomal Storage Disorders (LSDs) in India are facing a humanitarian crisis. In a letter to Prime Minister Narendra Modi and Health Minister J.P. Nadda, led by IMPF chairperson Anil Bonde, they called for urgent action. The problem stems from interruptions in Enzyme Replacement Therapy (ERT), the only life-saving treatment for some LSD patients, under the National Policy for Rare Diseases (NPRD) 2021. Nearly 60 patients have gone over the ₹50 lakh annual funding limit, halting their treatment. About 100 more who rely on regular ERT are now at risk as funds remain blocked. Shockingly, over 60 children and young adults have already died because of treatment delays or breaks, the forum said. The IMPF stressed that even short gaps in treatment cause irreversible organ damage or fatal metabolic crises. They demanded the government remove or greatly increase the ₹50 lakh funding cap for LSD patients. The forum also recommended a secure and predictable funding system and faster fund use at Centres of Excellence to stop dangerous delays. The IMPF's message is clear: urgent policy changes are needed to save lives and honor the promises of NPRD 2021. Without swift action, more children with these rare diseases could perish from preventable causes.